Thursday, April 04, 2013

Journal Alert - JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY

> Title:
> Parallel psychometric and cognitive modeling analyses of the Penn Face Memory Test in the Army Study to Assess Risk and Resilience in Servicemembers
>
> Authors:
> Thomas, ML; Brown, GG; Gur, RC; Hansen, JA; Nock, MK; Heeringa, S;
> Ursano, RJ; Stein, MB
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):225-245; MAR 1 2013
>
> Abstract:
> Objective: The psychometric properties of the Penn Face Memory Test
> (PFMT) were investigated in a large sample (4,236 participants) of U.S.
> Army Soldiers undergoing computerized neurocognitive testing. Data were
> drawn from the initial phase of the Army Study to Assess Risk and
> Resilience in Servicemembers (Army STARRS), a large-scale study directed
> towards identifying risk and resilience factors for suicidal behavior
> and other stress-related disorders in Army Soldiers. In this paper, we
> report parallel psychometric and cognitive modeling analyses of the PFMT
> to determine whether ability estimates derived from the measure are
> precise and valid indicators of memory in the Army STARRS sample.
> Method: Single-sample cross-validation methodology combined with
> exploratory factor and multidimensional item response theory techniques
> were used to explore the latent structure of the PFMT. To help resolve
> rotational indeterminacy of the exploratory solution, latent constructs
> were aligned with parameter estimates derived from an unequal-variance
> signal detection model. Results: Analyses suggest that the PFMT measures
> two distinct latent constructs, one associated with memory strength and
> one associated with response bias, and that test scores are generally
> precise indicators of ability for the majority of Army STARRS
> participants. Conclusions: These findings support the use of the PFMT as
> a measure of major constructs related to recognition memory and have
> implications for further cognitivepsychometric model development.
>
> ========================================================================
>
>
> *Pages: 246-258 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900002
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>
> Title:
> Association between cerebral metabolism and ReyOsterrieth Complex Figure Test performance in Alzheimer's disease
>
> Authors:
> Melrose, RJ; Harwood, D; Khoo, T; Mandelkern, M; Sultzer, DL
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):246-258; MAR 1 2013
>
> Abstract:
> The copy condition of the ReyOsterrieth Complex Figure (ROCF) is
> sensitive to Alzheimer's disease (AD) pathology, but its neural
> correlates remain unclear. We used fluorodeoxyglucose positron emission
> tomography (FDGPET) to elucidate this association in 77 patients with
> probable AD. We observed a correlation between ROCF and metabolic rate
> of bilateral temporalparietal cortex and occipital lobe, and right
> frontal lobe. Global and local elements of the ROCF correlated with
> metabolic rate of these same regions. The copy approach correlated with
> right lateral temporal cortex. The ROCF appears reflective of posterior
> temporalparietal cortex functioning, highlighting the role of
> visuospatial processing in constructional abilities in AD.
>
> ========================================================================
>
>
> *Pages: 259-268 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900003
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>
> Title:
> Action and noun fluency testing to distinguish between Alzheimer's disease and dementia with Lewy bodies
>
> Authors:
> Delbeuck, X; Debachy, B; Pasquier, F; Moroni, C
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):259-268; MAR 1 2013
>
> Abstract:
> The objective of the present study was to establish whether performance
> in an action fluency task is of value in the differential diagnosis of
> Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). After
> collecting normative data on performance in an action fluency task and a
> conventional animal fluency task in a cohort of French-speaking healthy
> controls, we assessed AD and DLB patients. Only the action fluency score
> differed significantly between the two demented groups, with DLB
> patients performing worse than AD patients. However, a composite action
> and animal fluency score was found to be more effective for
> discriminating between these two groups.
>
> ========================================================================
>
>
> *Pages: 269-278 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900004
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>
> Title:
> Confirmatory factor analysis of the Neuropsychological Assessment Battery of the LADIS study: A longitudinal analysis
>
> Authors:
> Moleiro, C; Madureira, S; Verdelho, A; Ferro, JM; Poggesi, A; Chabriat,
> H; Erkinjuntti, T; Fazekas, F; Hennerici, M; O'Brien, J; Pantoni, L;
> Salvadori, E; Scheltens, P; Visser, MC; Wahlund, LO; Waldemar, G;
> Wallin, A; Inzitari, D
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):269-278; MAR 1 2013
>
> Abstract:
> Age-related white matter changes have been associated with cognitive
> functioning, even though their role is not fully understood. This work
> aimed to test a 3-factor model of the neuropsychological assessment
> battery and evaluate how the model fit the data longitudinally.
> Confirmatory factor analysis (CFA) was used to investigate the
> dimensions of a structured set of neuropsychological tests administered
> to a multicenter, international sample of independent older adults
> (LADIS study). Six hundred and thirty-eight older adults completed
> baseline neuropsychological, clinical, functional and motor assessments,
> which were repeated each year for a 3-year follow-up. CFA provided
> support for a 3-factor model. These factors involve the dimensions of
> executive functions, memory functions, and speed and motor control
> abilities. Performance decreased in most neuropsychological measures.
> Results showed that executive functioning, memory and speed of motor
> abilities are valid latent variables of neuropsychological performance
> among older adults, and that this structure is relatively consistent
> longitudinally, even though performance decreases with time.
>
> ========================================================================
>
>
> *Pages: 279-290 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900005
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>
> Title:
> Event-based prospective memory and everyday forgetting in healthy older adults and individuals with mild cognitive impairment
>
> Authors:
> Tam, JW; Schmitter-Edgecombe, M
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):279-290; MAR 1 2013
>
> Abstract:
> An event-based nonfocal task was used to evaluate prospective memory
> (PM) and the relationship between PM, neuropsychological testing data,
> and everyday forgetting. Twenty-four participants with mild cognitive
> impairment (MCI) and 24 age- and education-matched cognitively healthy
> adults responded to a nonfocal PM cue, while completing an ongoing
> working memory task. Neuropsychological testing data and self- and
> informant-report of frequency of forgetting were also gathered. Compared
> to healthy adults, the MCI participants exhibited significantly poorer
> prospective remembering and ongoing task performance, despite similar
> self-reported effort directed to the PM task. Both self- and
> informant-report indicated that the MCI group was experiencing a higher
> frequency of everyday forgetting than the healthy adult group.
> Self-report of everyday forgetting was correlated with PM task
> performance for the healthy adults, but not for the MCI participants.
> For the healthy adults, correlational analyses also showed significant
> relationships between PM accuracy and tests of memory and executive
> functioning, suggesting that both spontaneous retrieval processes and
> effortful, strategic monitoring may be important in supporting
> prospective remembering for this nonfocal PM task. The stronger
> relationships between PM accuracy and memory and language tests for the
> MCI group suggest that their poorer event-based prospective remembering
> might be linked to impaired spontaneous retrieval processes, which are
> thought to be supported by medial temporal structures.
>
> ========================================================================
>
>
> *Pages: 291-297 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900006
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>
> Title:
> The blindside: Impact of monocular occlusion on spatial attention
>
> Authors:
> Burtis, DB; Williamson, JB; Mishra, M; Heilman, KM
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):291-297; MAR 1 2013
>
> Abstract:
> Monocular occlusion has been posited to reduce activation of the
> contralateral hemisphere (Sprague effect), thus inducing a contralateral
> spatial bias (toward the viewing eye). Healthy right-handed participants
> bisected horizontal lines during monocular eye viewing. Although
> subjects tended to deviate away from the viewing eye, only left-eye
> viewing deviated significantly right of midline. These results suggest
> that eye patching may induce an attentional compensation similar to that
> in hemianopic patients. Alternatively, increased activation of higher
> cortical regions mediating spatial attention in contralateral hemispace
> may be an adaptive response to decreased activation of its ipsilateral
> superior colliculus induced by contralateral eye patching.
>
> ========================================================================
>
>
> *Pages: 298-308 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900007
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>
> Title:
> Does the presence of posttraumatic anosmia mean that you will be disinhibited?
>
> Authors:
> Crowe, SF; Crowe, LM
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):298-308; MAR 1 2013
>
> Abstract:
> Dispute has surrounded the issue of whether the relationship between
> anosmia and executive dysfunction in traumatic brain injury (TBI) may be
> artefactual due to poor ascertainment. Three groups matched for age,
> gender, education, Full Scale IQ, and the Wechsler Working Memory Index
> and showing adequate symptom validity were compared: 30 anosmic TBIs
> (TBI-A) matched for posttraumatic amnesia (PTA) and working memory
> functioning with 36 nonanosmic TBIs (TBI-NA) and 51 controls. The groups
> performed the FAS test, the Animal Fluency test, the Stroop Neurological
> Screening Test (SNST), the Wisconsin Card Sorting Test64 (WCST64) and
> the Trail Making Test (TMT-B) as well as tests of emotional functioning
> and return to work outcome. After adjusting for the covariates (i.e.,
> gender; Wechsler Test of Adult Reading, WTAR; and years of education), a
> significant effect was found for items successfully completed on the
> SNST, the FAS task, the Animal Fluency task, and the WCST64 categories
> completed. After adjusting for the covariates, a significant difference
> was found for number of errors on the SNST and for the number and type
> of errors on TMT-B. The two groups did not differ in terms of their
> affective functioning (i.e., Beck Depression Inventory or Beck Anxiety
> Inventory), or in terms of their outcome with regard to return to work.
> The findings support the notion that the TBI-A group demonstrated
> considerably weaker performance on executive tasks than did the
> nonanosmic TBIs. These patients were not, however, more prone to an
> error-prone pattern of performance, and, if anything, their executive
> deficit was more likely attributable to a reduced productivity of
> response.
>
> ========================================================================
>
>
> *Pages: 309-318 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900008
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>
> Title:
> The adverse impact of type 2 diabetes on brain volume in heart failure
>
> Authors:
> Alosco, ML; Brickman, AM; Spitznagel, MB; Griffith, EY; Narkhede, A;
> Raz, N; Cohen, R; Sweet, LH; Colbert, LH; Josephson, R; Hughes, J;
> Rosneck, J; Gunstad, J
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):309-318; MAR 1 2013
>
> Abstract:
> Objective: Heart failure (HF) is associated with structural brain
> abnormalities, including atrophy in multiple brain regions. Type 2
> diabetes mellitus (T2DM) is a prevalent comorbid condition in HF and is
> associated with abnormalities on neuroimaging in other medical and
> elderly samples. The current study examined whether comorbid T2DM
> exacerbates brain atrophy in older adults with HF. Methods: Seventy-five
> older adults with HF underwent an echocardiogram and completed a brief
> cognitive test battery. Participants then underwent brain magnetic
> resonance imaging (MRI) to quantify total brain volumes, cortical lobar
> volumes, and white matter hyperintensities (WMH). Results: Approximately
> 30% of HF patients had a comorbid T2DM diagnosis. A series of
> multivariate analyses of covariance (MANCOVAs) adjusting for medical and
> demographic characteristics and intracranial volume showed that HF
> patients with T2DM had smaller total brain, gray matter, and subcortical
> gray matter volume than those without such history. No between-group
> differences emerged for WMH. Persons with T2DM also had smaller cortical
> lobar volumes, including in frontal, temporal, and parietal lobes.
> Follow-up analyses revealed that smaller total and cortical lobar brain
> volumes and WMH were associated with poorer performance on measures of
> global cognitive status, attention, executive functions, and memory.
> Conclusions: T2DM is associated with smaller total and cortical lobar
> brain volumes in patients with HF, and these structural brain indices
> were associated with cognitive test performance. Prospective studies
> that directly monitor glucose levels are needed to confirm our findings
> and clarify the mechanisms by which T2DM adversely impacts brain atrophy
> in this population.
>
> ========================================================================
>
>
> *Pages: 319-328 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900009
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>
> Title:
> A comparison of the Cambridge Automated Neuropsychological Test Battery (CANTAB) with "traditional" neuropsychological testing instruments
>
> Authors:
> Smith, PJ; Need, AC; Cirulli, ET; Chiba-Falek, O; Attix, DK
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):319-328; MAR 1 2013
>
> Abstract:
> The Cambridge Neuropsychological Test Automated Battery (CANTAB) is
> frequently used in research protocols and increasingly in clinical
> practice. Despite the frequency of its use, important aspects of its
> measurement validity have yet to be established in healthy adults. Two
> hundred and fifty-five individuals completed the CANTAB and traditional
> neuropsychological tests commonly used in clinical practice, including
> selected subtests from the Wechsler Adult Intelligence Scale, Controlled
> Oral Word Association Test, Animal Naming, Trail Making Tests A and B,
> the Stroop test, and the Green Story Recall test. Results showed that
> CANTAB subtests were modestly correlated with traditional subtests.
> Correlations between CANTAB subtests and traditional subtests were less
> consistent when age and education were controlled for. In conclusion,
> the CANTAB shows modest associations with traditional neuropsychological
> test measures.
>
> ========================================================================
>
>
> *Pages: 329-336 (Article)
> *View Full Record: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=CCC&DestLinkType=FullRecord;KeyUT=CCC:000315985900010
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>
> Title:
> Ecological validity of the Multiple Errands Test using predictive models of dysexecutive problems in everyday life
>
> Authors:
> Cuberos-Urbano, G; Caracuel, A; Vilar-Lopez, R; Valls-Serrano, C;
> Bateman, A; Verdejo-Garcia, A
>
> Source:
> *JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY*, 35 (3):329-336; MAR 1 2013
>
> Abstract:
> Thedysexecutive syndrome is composed of a range of cognitive, emotional,
> and behavioral deficits that are difficult to evaluate using traditional
> neuropsychological tests. The Multiple Errands Test (MET) was originally
> developed to systematize the assessment of the more elusive
> manifestations of the dysexecutive syndrome. The aims of this study were
> to examining the reliability of the MET and to investigate the
> predictive ability of its indices to explain a range of
> dysexecutive-related symptoms in everyday life. Thirty patients with
> acquired brain injury participated in this study. The MET showed an
> adequate inter-rater reliability and ecological validity. The main
> performance indices from the MET were able to significantly predict
> severity of everyday life executive problems, with different indices
> predicting particular manifestations of different components of
> executive functions.
>
>

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