Saturday, February 07, 2026

Research alert: Executive functions and psychopathology: A transdiagnostic network analysis - #networkanalysis #executivefunctions #Gwm #AC #workingmemory #attentionalcontrol #psychopathology #schoolpsychologists #schoolpsychology #AC-Gwmcomplex

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Following up on my post the other day that suggests that the AC-Gwm (attentional control-working memory) complex is key to cognitive functioning, a new article implicating the same complex in preadolescent psychopathology.  It is becoming more clear that the AC-Gwm complex is central key for understanding a variety of human behaviors.  




Open access article available here.


Abstract

Mental health research is shifting toward dimensional, transdiagnostic frameworks, yet the role of executive functions (EFs) across psychopathological domains remains unclear. In this study, we examined transdiagnostic associations and potential directional pathways linking EFs with psychopathology in a large sample of preado-lescents (N = 9,119) from the Adolescent Brain Cognitive Development (ABCD) study. We employed a Gaussian graphical model (GGM) to estimate partial correlations and a directed acyclic graph (DAG) to infer potential directional influences between EFs and psychopathology. Modest associations were observed among the EFs and psy-chopathology. Working memory emerged as a central node, showing positive asso-ciations with attention problems, social problems, and rule-breaking behavior, and negative associations with anxious/depressed and somatic complaints. These results were mirrored in the DAG, which identified working memory and attention problems as key converging hubs. Sex-stratified analyses revealed notable differences in net-work structure. Our findings reveal a core transdiagnostic role for working memory in preadolescent psychopathology.