Showing posts with label ADHD. Show all posts
Showing posts with label ADHD. Show all posts

Friday, March 21, 2025

Research Byte: Co-Occurrence and Causality Among #ADHD, #Dyslexia, and #Dyscalculia - #SLD #schoolpsychology #sped #genetics #EDPSY

Co-Occurrence and Causality Among ADHD, Dyslexia, and Dyscalculia

Published in Psychological Science.  Click here to access PDF copy of article

Abstract
ADHD, dyslexia, and dyscalculia often co-occur, and the underlying continuous traits are correlated (ADHD symptoms, reading, spelling, and math skills). This may be explained by trait-to-trait causal effects, shared genetic and environmental factors, or both. We studied a sample of ≤ 19,125 twin children and 2,150 siblings from the Netherlands Twin Register, assessed at ages 7 and 10. Children with a condition, compared to those without that condition, were 2.1 to 3.1 times more likely to have a second condition. Still, most children (77.3%) with ADHD, dyslexia, or dyscalculia had just one condition. Cross-lagged modeling suggested that reading causally influences spelling (β = 0.44). For all other trait combinations, cross-lagged modeling suggested that the trait correlations are attributable to genetic influences common to all traits, rather than causal influences. Thus, ADHD, dyslexia, and dyscalculia seem to co-occur because of correlated genetic risks, rather than causality.



 

Saturday, July 14, 2018

Using Gt distribution parameters to predict executive functions in AHDH: Study consistent with Schneider & McGrew 2018 CHC update chapter

Interesting article consistent with what Joel Schneider and I discussed in our latest CHC Intelligence theory update chapter. Click here for info.

Using inspection time and ex-Gaussian parameters of reaction time to predict executive functions in children with ADHD. Intelligence, 69 (2018) 186–194.

Hilary Galloway-Long, Cynthia Huang-Pollock


A B S T R A C T

Slower and more variable performance in speeded reaction time tasks is a prominent cognitive signature among children with Attention Deficit Hyperactivity Disorder (ADHD), and is often also negatively associated with executive functioning ability. In the current study, we utilize a visual inspection time task and an ex-Gaussian decomposition of the reaction time data from the same task to better understand which of several cognitive subprocesses (i.e., perceptual encoding, decision-making, or fine-motor output) may be responsible for these important relationships. Consistent with previous research, children with ADHD (n = 190; 68 girls) had longer/ slower SD and tau than non-ADHD peers (n = 76; 42 girls), but there were no group differences in inspection time, mu, or sigma. Smaller mu, greater sigma, longer tau, and slower inspection time together predicted worse performance on a latent executive function factor, but only tau partially mediated the relationship between ADHD symptomology and EF. These results suggest that the speed of information accumulation during the decision-making process may be an important mechanism that explains ADHD-related deficits in executive control.

Click image to enlarge.



Assessment Recommendations for Gt (from Schneider & McGrew, 2018)

To be published shortly in:




Tasks measuring Gt are not typically used in clinical settings (except perhaps in CPTs). With the increasing use of low-cost mobile computing devices (i.e., smartphones and iPads/other slate notebook computers), we predict that practical measures of Gt will soon be available for clinical use. Some potential clinical applications are already apparent. We present three examples.

Gregory, Nettelbeck, and Wilson (2009) demonstrated that initial level of and rate of changes in inspection time might serve as an important biomarker of aging. Briefly, a biomarker for the aging process “is a biological parameter, like blood pressure or visual acuity that measures a basic biological process of ageing and predicts later functional capabilities more effectively than can chronological age . . . a valid biomarker should predict a range of important age-related outcomes including cognitive functioning, everyday independence and mortality, in that order of salience” (p. 999). In a small sample of elderly individuals, initial inspection time level and rate of slowing (over repeated testing) was related to cognitive functioning and everyday competence. Repeated, relatively low-cost assessment of adults' inspection times might serve a useful function in cognitive aging research and serve as a routine measure (much like blood pressure) to detect possible early signs of cognitive decline.

Researchers have demonstrated how to harness the typical non-normal distributions of RT as a potential aid in diagnosis of certain clinical disorders. Most RT response distributions are not normally distributed in the classic sense. They are virtually always positively skewed, with most RTs falling at the faster end of the distribution. These distributions are called ex-Gaussian, which is a mathematical combination of Gaussian and exponential distributions. It can be characterized by the mean (m), the standard deviation (s),and an exponential function (t) that reflects the mean and standard deviation exponential component (Balota & Yap, 2011). (Don't worry; one does not need to under-stand this statistics-as-a-second-language brief description to appreciate the potential application.) The important finding is that “individuals carry with them their own characteristic RT distributions that are relatively stable over time” (p. 162). Thus, given the ease an efficiency with which RT tests could be repeatedly administered to individu-als (via smart devices and portable computers), it would be possible to readily obtain each person's RT distribution signature. Of most importance is the finding that all three RT distribution parameters are relatively stable, and t is very stable (e.g., test–retest correlations in the high .80s to low .90s). Furthermore, there is a robust relation between t and working memory performance that is consistent with the worst-performance rule (WPR) discovered in the intelligence literature. The WPR states that on repeated trial testing on cognitive tasks, the trials where a person does poorest (worst) are better predictors of intelligence than the best-performance trials (Coyle, 2003). It has been demonstrated, in keeping with the WPR, that the portion of each person's RT distribution representing the slowest RTs is strongly related to fluid intelligence and working memory.

In the not-too-distant future, assessment personal armed with portable smart devices or computers could test an individual repeatedly over time with RT paradigms. Then, via magical software or app algorithms, a person's RT distribution signature could be obtained (and compared against the normative distribution) to gain insights into the person's general intelligence, Gf, or working memory over time. This could have im-portant applications in monitoring of age-related cognitive changes, responses to medication for attention-deficit/hyperactivity disorder (ADHD) or other disorders, the effectiveness of brain fitness programs, and so forth. Finally, using the same general RT paradigms and metrics, research has indicated that it may be possible to differentiate children with ADHD from typically developing children (Kofler et al., 2013) and children with ADHD from those with dyslexia (Gooch, Snowling, & Hulme, 2012), based on the RT variability—not the mean level of performance. It is also possible that RT variability might simply be a general marker for a number of underlying neurocognitive disorders.

We have the technology. We have the capability to build portable, low-cost assessment technology based on Gt assessment paradigms. With more efficient and better assessments than before, build it . . . and they (assessment professionals) will come.


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Saturday, January 16, 2016

Thursday, January 07, 2016

Research byte: Working memory (Gwm), Gs (processing speed), fluid intelligence (Gf) and ADHD

Working memory – not processing speed – mediates fluid intelligence deficits associated with attention deficit/hyperactivity disorder symptoms

  1. Christopher R. Brydges1,2,*,
  2. Krista L. Ozolnieks1 and
  3. Gareth Roberts1
Article first published online: 31 DEC 2015
DOI: 10.1111/jnp.12096
Journal of Neuropsychology

Journal of Neuropsychology


Keywords:

  • attention deficit/hyperactivity disorder;
  • fluid intelligence;
  • working memory;
  • processing speed

Abstract

Attention deficit/hyperactivity disorder (ADHD) is a psychological condition characterized by inattention and hyperactivity. Cognitive deficits are commonly observed in ADHD patients, including impaired working memory, processing speed, and fluid intelligence, the three of which are theorized to be closely associated with one another. In this study, we aimed to determine if decreased fluid intelligence was associated with ADHD, and was mediated by deficits in working memory and processing speed. This study tested 142 young adults from the general population on a range of working memory, processing speed, and fluid intelligence tasks, and an ADHD self-report symptoms questionnaire. Results showed that total and hyperactive ADHD symptoms correlated significantly and negatively with fluid intelligence, but this association was fully mediated by working memory. However, inattentive symptoms were not associated with fluid intelligence. Additionally, processing speed was not associated with ADHD symptoms at all, and was not uniquely predictive of fluid intelligence. The results provide implications for working memory training programs for ADHD patients, and highlight potential differences between the neuropsychological profiles of ADHD subtypes.

Thursday, August 13, 2015

More research suggesting ADHD may be due (in part) to an internal brain clock disorder


Another study linking distorted time-processing and ADHD.  Click here and here for posts about other related studies.  What I find interesting is that the various experimental timing measures used in these studies could easily be made into psychometric tests (with readily available technology) for inclusion on intelligence tests or other special purpose cognitive batteries.  Also, I have hypothesized in a MindHub Pub that some emerging neurotechnologies may improve ADHD (and related symptoms like attentional control and working memory) due to the fine-tuning of the human brain clock.

Other ADHD related research (brain connectivity, etc) can be found here.

Click on image to enlarge for easier reading,

Sunday, September 21, 2014

ADHD: And even MORE evidence suggestive of a brain network connectivity disorder

And more evidence for ADHD as being related to poor brain network connectivity. (click here for more posts) Click on images to enlarge.






And, again, this extant research is consistent with the three-level hypothesized explanation of the impact of certain brain training programs on controlled attention (click here for special white paper as well as on-line PPT modules and keynote video presentation of this model).




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Tuesday, July 29, 2014

ADHD as a brain network disorder: More evidence




It is becoming clear that ADHD is likely related to dysfunctional interactions between certain brain networks (click here for prior ADHD posts). The following two studies add to this growing literature on the importance of brain network connectivity.

This research is also consistent with my previously posted white-paper on brain networks, temporal processing (brain clock) and cognitive efficiency processing with a strong influence of white matter integrity (paper is written around explaining the efficacy of the IM intervention but can also be viewed as a three level explanation of how brain networks influence working memory, attentional control, and executive functioning).

Click on images to enlarge.














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Sunday, July 08, 2012

Research byte: More on ADHD as a default brain network disorder




This is one of the first studies to suggest that some forms of ADHD may be due to altered brain network functioning, specifically a disorder in the default brain network (or other networks that control the default mode network. Click here for prior posts re: this hypothesis. [Click on image to enlarge]





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www.themindhub.com

Sunday, May 06, 2012

EDDA 2012 ADHD newsletter article




Newsletter article regarding 2012 Las Vegas conference available here.

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www.themindhub.com

Wednesday, March 28, 2012

ADHD as a default brain network disorder




Some interesting research regarding the role of the default mode or default brain network and ADHD. Although the blog post is at the IM-HOME blog (conflict of interest - I am an external consultant to IM in the capacity as Director of Research and Science), most of the links are to other non-IM articles regarding the ADHD/default link. The Neuropsychopharm. article link and the link back to an annotated article (at the Brain Clock blog) published in Trends in Cognitive Science are important...IMHO


Sent from Kevin McGrew's iPad
Kevin McGrew, PhD
Educational Psychologist




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Sunday, March 11, 2012

ADHD as a default brain network problem?







Trends in Cognitive Sciences, January 2012, Vol. 16, No. 1

I just skimmed this excellent article which is consistent with the hypothesis that problems with controlled attention (focus) may be responsible for a number of the behavioral symptoms of ADHD....and this is due to the poor ability to suppress the random self-talk of the default brain network. As per the IQs Reading feature, an annotated copy of the article is now available.

Based on my reading and research regarding Interactive Metronome technology, I advanced the position that the efficacy of this technology in improving focus or controlled attention is that it helps to "quiet the busy mind" that is due to the REST (random, episodic, spontaneous thought or thinking) of the default brain network. In simple terms, poor ability to suppress or quiet the default network results in poor controlled attention and focus...and one has a hard time with inhibiting the intrusion of these task-irrelevant thoughts when trying to engage in controlled, deliberate cognitive tasks.

This article reviews research that suggests that ADHD may be a default brain network disorder. The authors state "In 2007, Sonuga-Barke and Castellanos suggested that ADHD could be considered a default network disorder"...and the authors of the current article agree.


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Friday, January 27, 2012

Research bytes: ADHD diagnosis--gender and adolescence

Double click on images to enlarge






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Sunday, August 21, 2011

Tuesday, June 14, 2011

Research byte: Working memory model of ADHD

Click on images to enlarge











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Tuesday, December 07, 2010

Research byte: No "pay attention"




kanas, K. N., Colombo, J., & Wyss, N. (2010). Now, Pay Attention! The Effects of Instruction on Children's Attention. Journal of Cognition and Development, 11(4), 509-532

Abstract

We investigated the effects of instructions to “stay on task” on preschoolers' attention and cognitive performance in the face of either incomprehensible or comprehensible distraction. Three- and 4-year-olds completed problem-solving tasks while a distracting event played continuously in the background under conditions of a) no instruction, b) moderate instruction, or c) frequent instruction to “stay on task.” Under conditions where an incomprehensible distractor was present, any amount of instruction reduced looking to the distracting event. Under conditions where a comprehensible distractor was present, however, frequent instruction was the most effective in increasing looking to the task and decreasing looking to the distracting event.


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